![]() ![]() Without mature B lymphocytes, antibody-producing plasma cells are also absent. In the absence of BTK, B lymphocytes do not differentiate or mature. X-linked agammaglobulinemia (XLA) or Bruton agammaglobulinemia, is an inherited immunodeficiency disease caused by mutations in the gene BTK, that codes for Bruton tyrosine kinase (BTK). SCIG is a valuable choice for treating XLA patients, even from the very beginning.ĭisease Bruton, X-linked agammaglobulinemia, Immunoglobulins, Immunodeficiency Parental evaluation of quality of life is good. IgG levels rose over 700 mg/dL, and infections disappeared. A new aim of IgG over 700 mg/dLwas established, after current recommendations. Nevertheless, 15 months later, IgG levels fell below 500 mg/dL, and some infections occurred. Initially, the aim was trough serum IgG over 500 mg/dL. A loading dose of 6 g, in three consecutive days (2 g/day) was prescribed. Our aim was to describe our experience with SCIG from the diagnosis in a patient with X-linked agammaglobulinemia (XLA).Ī recently diagnosed 6-year-old child with XLA was started on SCIG. Wasserman Peter V.Subcutaneous immunoglobulin (SCIG) utilization is limited in Spain. Civilization and its Discontents (Sigmund Freud).Interpersonal Communication (Kory Floyd). ![]()
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